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    ~~~  WHAT  IS  OXIDATIVE  THERAPY  ~~~
	1-  the administration of oxidants 
	    in the treatment of illness or 
	    for other healthful purposes; 
	2-  the promoting, accelerating, 
	    supplementing, or stimulating 
	    of oxidative processes in the body. 


   ~~~ OXIDATIVE THERAPY =/= FREE RADICAL STRESS ~~~
"Oxidative Therapy" is NOT the same as "Free Radical Stress". 
Oxidative Therapy is not meant to be destructive. 
Safe physiologic changes are preferred, such as: 
	- a shift in redox potential, 
	- altered utilization of reducing equivalents, 
	- on/off switching of cellular controls 
Free Radical Stress is characterized by: 
	- a toxic overabundance of oxyradicals, 
	- damage to biomolecules and to cellular structures 

   ~~~  MYTHS PERTAINING TO BIOLOGICAL OXIDATION  ~~~

         FACTS:                               MYTHS:
1- Many oxyradicals are          1- Therefore all oxidants are 
   strong oxidants and toxic.       toxic just like oxyradicals. 
2- Oxyradicals are free          2- Therefore all free 
   radicals and often toxic.        radicals are toxic. 
3- Certain quenchers of          3- Therefore a reductant overload 
   oxyradicals are reductants.      is beneficial to eliminate as 
                                    many oxidants as possible. 

~~~ TRUTHS PERTAINING TO OXIDANTS AND FREE RADICALS ~~~

1. THERE ARE GOOD OXIDANTS:
	cytochromes, ubiquinone, flavoproteins, 
	pyridinium nucleotides, amine oxidases, 
	pyrroloquinoline quinone, disulfides, 
	diatomic oxygen, hydrogen peroxide, etc. 

2. THERE ARE GOOD FREE RADICALS:
	semioxidized ascorbate, semireduced flavins, 
	tocopheryl, nitric oxide, superoxide, etc. 

3.  THERE  ARE  BAD  REDUCTANTS:
	hyperglycemia, acetaldehyde, tyramine, 
	ferrous iron, methyl mercury, etc. 

     ~~~  OXYGENATION  VERSUS  OXIDATION  ~~~
	OXYGENATION:
 The physiologic process of absorbing diatomic 
 oxygen (O2) and delivering it to tissues. 
	OXIDATION:
 The physiologic process of accepting, 
 taking up, or removing electrons. 

  ~~~  FACTORS  WHICH  INHIBIT  OXYGENATION  ~~~
	-  Poor Air Quality 
	-  High Altitude 
	-  Poor Lung Function 
	-  Anemia 
	-  RBC Clumping 
	-  Hemoglobinopathy 
		methemoglobin 
		carboxy hemoglobin 
		2,3-DPG deficiency 
	-  Arterial Stenosis 
	-  Arteriolar Vasospasm 
	-  Capillary Endothelial Swelling 
	-  Fibrin Layering 
	-  Basement Membrane Thickening 
	-  Tissue Swelling 
	-  Cytochrome A3 Dysfunction 
		copper deficiency 
		CO, CN-, HS-, NN-
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